题名：Alizarin Red–Tb3+ complex as a ratiometric colorimetric and fluorescent dual probe for the smartphone-based detection of an anthrax biomarker

来源：Analytical Methods

发表年代：2019年

作者：Miao Xu, Wei Huang, Dingkun Lu, Chunyu Huang, Jingjing Deng * , Tianshu Zhou

Abstract  In this work, a novel dual-sensing probe was developed for detecting an anthrax biomarker (dipicolinic acid, DPA) based on the competitive coordination of Tb³⁺ between DPA and Alizarin Red (AR). UV-vis titration experiments demonstrated that AR and Tb³⁺ ions formed a 3 : 1 coordination pair in a boric acid–borate buffer solution. However, the subsequent addition of DPA to the complex solution destroyed the coordination of AR–Tb³⁺ completely, resulting in the formation of DPA–Tb³⁺. This constructed a new mechanism of ratiometric colorimetric and fluorescence dual-mode sensing for DPA. By integrating a smartphone with an easy-to-access color-scanning APP, this dual-sensing method could be further applied as a reliable scanometric assay for the rapid and on-site visible detection of DPA directly. With the method established by us, the sensitive and selective detection of DPA released from bacterial spores could be realized easily.

Alizarin-RedTb3-complex-as-a-ratiometric-colorimetric-and-fluorescent-dual-probe-for-the-smartphonebased-detection-of-an-anthrax-biomarkerAnalytical-Methods.pdf